ClinicalTrials.gov Query Generator in EasySLR

ClinicalTrials.gov Query Generator in EasySLR

The ClinicalTrials.gov Query Generation tool in EasySLR helps you create a structured, ready-to-use search strategy for clinical trial registries in just a few steps. By leveraging AI and the PICOS framework, the tool saves time, improves consistency, and ensures your clinical trials search is aligned with your research objective.

When to Use This Tool
Use the ClinicalTrials.gov Query Generator when:
  • Starting a systematic review and identifying ongoing or completed clinical trials
  • Ensuring all relevant PICOS terms are captured in your clinical trials search
  • Quickly adapting or refining trial search strategies for different research topics
  • Preparing search strategies for registries such as ClinicalTrials.gov or WHO ICTRP

How to Generate a Clinical Trials Search Query
  1. Select Clinical Trials Query Generation in Tools.


  1. Click Generate Search Queries.
  2. Add your Research Objective.

  1. Validate the Research Objective using the Validate option to ensure all relevant
     PICOS (Population, Intervention, Comparator, Outcomes, Study Design) terms are included.

  2. Add Key Trials for Maximum Recall (optional but recommended) to help optimize recall and ensure important trials are reflected in the generated terms.

Refining Your Search Terms
The tool automatically generates PICOS-based search terms suitable for clinical trial searches.
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You can:
  • Edit terms to make them broader or more specific
  • Add custom terms to capture unique aspects of your research topic
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Always review and refine the generated query before running it in a trial registry.
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Running the Clinical Trials Search
Unlike PubMed, clinical trial registries are not directly integrated with EasySLR.
  • Copy the generated query
  • Run it manually in ClinicalTrials.gov

Importing Clinical Trial Records into EasySLR
When you click on the "Import Trials" button, you’ll be redirected to another window where you can:
  • Select a Publication Year range to narrow your import.

Important Note on AI Usage
While AI features can assist and speed up the review process, users should be aware that large language models (LLMs) may produce incomplete or incorrect results. Clear and well-defined protocols are essential for reliable AI support. All AI-generated outputs should be carefully reviewed, and final judgment and decision-making responsibility always rests with human reviewers.
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Best Practices & Tips
  • Always review generated queries before importing trials
  • Use clear and specific PICOS definitions to avoid irrelevant trials
  • Add Key Articles to improve recall and alignment with known evidence
  • Maintain consistency between protocol definitions and generated queries

Troubleshooting
No results generated?
  • Check your AI credit balance
  • Refine or clarify your research objective
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Low recall?
  • Add more key trial ids
  • Broaden PICOS terms
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Too many irrelevant results?
  • Narrow terms
  • Add exclusions or increase specificity
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Benefits of the Clinical Trials Query Generation Tool
  • Saves time spent manually drafting trial registry queries
  • Ensures consistent use of the PICOS framework
  • Helps identify ongoing, completed, or unpublished trials
  • Easy to refine and adapt as project needs evolve

Q. Are AI credits charged when I generate a clinical trials search query?
 Yes. 200 AI credits are consumed each time you generate a new query.


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